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Cutivate Lotion and Pregnancy

When steroids, including Cutivate Lotion (fluticasone propionate lotion), were given to pregnant animals, the drug increased the risk for birth defects, poor fetal growth, and reduced survival rates. However, it is unknown if similar problems would occur in humans. It is probably best for pregnant women to avoid using Cutivate Lotion over a large area for extended periods.

Can Pregnant Women Use Cutivate Lotion?

Cutivate Lotion® (fluticasone propionate lotion) is a prescription topical steroid approved for treating atopic dermatitis in adults and children as young as 1 year old. Based on information currently available, it is unclear if the drug is safe for use during pregnancy. As with most medications, it should be used only if necessary, at the lowest effective dose, and for the shortest possible time during pregnancy.
 

What Is Pregnancy Category C?

Cutivate Lotion is classified as a pregnancy Category C drug. The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but have caused fetal harm in animal studies.
 
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
Animal studies have shown that steroids, including Cutivate Lotion, may increase the risk for birth defects (such as cleft palate) and may cause other problems, such as poor fetal growth or decreased survival. Similar problems might also occur in humans, although the risk is probably smaller for topical steroids that are applied to the skin like Cutivate Lotion.
 
While short-term use (a few days) of Cutivate Lotion applied to a small area of the body is probably not likely to cause problems, extended use or use over a large area of the body should probably be avoided during pregnancy if possible.
 
Pregnancy and Pain

Cutivate Lotion Medication Information

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