Precautions and Warnings With Clobetasol Propionate
Prior to starting treatment with clobetasol propionate, your healthcare provider needs to know if you are taking any other medications or if you have any allergies. Other safety precautions with clobetasol propionate include warnings of potentially serious reactions that may occur with long-term use. For instance, using this drug for extended periods may lead to diabetes or Cushing's syndrome.
You should talk with your healthcare provider prior to using clobetasol propionate (Clobex®, Cormax®, Olux®, Temovate®) if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Have any allergies, including to foods, dyes, or preservatives.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Some warnings and precautions to be aware of before using this medicine include the following:
- Clobetasol propionate is a steroid and can cause serious side effects, such as Cushing's syndrome or diabetes. Although this is more likely to occur with oral or injectable steroids, it is still possible with topical steroids, including clobetasol propionate. The more you apply and the longer you use the drug, the more likely these problems are to occur. Covering the medicine with a dressing may also increase the risk.
- If you use this medication for an extended period, it may lead to Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids). Contact your healthcare provider if you develop signs of this condition, such as:
- A rounded face
- Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
- High blood sugar levels.
- Clobetasol propionate can suppress the body's ability to make natural steroids. This typically happens when large doses are used over a long period. In such circumstances, the drug should be stopped gradually to give your body a chance to begin making its own natural steroids again. If this is not feasible, you might need to take an oral steroid for a while, after which you will slowly be weaned off it.
- For most circumstances, this medication is recommended only for up to two weeks of use. Although the drug is quite effective, it should not be used on a long-term basis due to the risk of serious side effects.
- Like all steroids, clobetasol propionate may slow down the growth rate of children and teenagers. Contact your child's healthcare provider if you are concerned about this. In general, children may be more susceptible to the side effects of steroids. Close monitoring is necessary for any child receiving long-term steroids. Because clobetasol propionate is a highly potent steroid, a less potent steroid might be a better option for children.
- Clobetasol propionate may react with a few other medications (see Drug Interactions With Clobetasol Propionate).
- This product is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Clobex and Pregnancy, Olux and Pregnancy, or Temovate and Pregnancy).
- It is unknown if clobetasol propionate passes through breast milk when applied to the skin. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drug (see Clobex and Breastfeeding, Olux and Pregnancy, or Temovate and Breastfeeding).