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More Info on Indications for Clindamycin/Benzoyl Peroxide

How Does Clindamycin/Benzoyl Peroxide Work?

As the name implies, clindamycin/benzoyl peroxide contains two active medicines: benzoyl peroxide and clindamycin. These two medicines work in different ways to stop Propionibacterium acnes (P. acnes), the bacteria that contribute to acne.
Clindamycin works by binding to bacterial ribosomes, which are the parts of cells that make proteins. This prevents the bacteria from making proteins, which are essential for the bacteria to grow and multiply.
Benzoyl peroxide is thought to work by releasing oxygen into the skin's pores. Because P. acnes is an anaerobe, which means it lives without oxygen, the oxygen kills the bacteria. Benzoyl peroxide also helps soften and peel away the outer layer of the skin, which may open up clogged pores and help improve the skin's appearance.

Can Children Use It?

Clindamycin/benzoyl peroxide is approved for use in people 12 years of age and older. It has not been adequately studied in children younger than 12. Talk with your child's healthcare provider about the benefits and risks of giving this medicine to your child.

Can Older Adults Use It?

Yes, clindamycin/benzoyl peroxide can be used in older adults. However, the clinical studies for this medicine generally included younger adults. It is unknown if older adults will respond to the medicine in the same way as younger age groups.

Is Clindamycin/Benzoyl Peroxide Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this product for something other than acne. This would be known as an "off-label" use. For example, using clindamycin/benzoyl peroxide in someone younger than 12 years of age would be considered an off-label use.

Clindamycin/Benzoyl Peroxide Information

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