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How Often Do Problems Occur With Clindamycin/Benzoyl Peroxide?

Common Side Effects of Clindamycin/Benzoyl Peroxide

Clindamycin/benzoyl peroxide has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in people using the drug were carefully documented and compared to those that occurred in people using a "placebo" gel (a gel without any active ingredients).
The exact side effects, and how commonly they occur, may vary depending on the actual clindamycin/benzoyl peroxide medicine used. In clinical trials, the most commonly reported side effects were related to the skin, including:
  • Redness of the skin -- in up to 31 percent of people
  • Peeling skin -- up to 19 percent
  • Dryness -- up to 16 percent
  • Itching -- up to 15 percent
  • Tingling, burning, or stinging -- up to 8 percent.

Other Possible Side Effects

Although occurring infrequently, other reactions to this medicine may include:
  • Sunburn
  • Pain at the application site
  • Sloughing of skin
  • Skin irritation.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using clindamycin/benzoyl peroxide or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.

Clindamycin/Benzoyl Peroxide Information

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