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Specific Drugs That React With Clemastine

Clemastine Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when clemastine is combined with any of the drugs listed above.
 
Alcohol
You should avoid alcohol while taking clemastine, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Acetylcholinesterase Inhibitor Medications
Taking clemastine with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring. Check with your healthcare provider before combining these medications.
 
Anticholinergic Drugs
Combining an anticholinergic medication with clemastine (which is also an anticholinergic medication) can increase your risk of clemastine side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine. Check with your healthcare provider before combining these medications.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking clemastine and an MAOI together can prolong and intensify certain side effects of clemastine (such as drowsiness, dry mouth, constipation, dry eyes, or difficulty passing urine). Check with your healthcare provider before combining these medications.
 
Other Medications That Cause Drowsiness
Check with your healthcare provider before combining clemastine with any other medication that also causes drowsiness, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Phenothiazines
It is possible that clemastine may increase the risk of a dangerous irregular heart rhythm (arrhythmia) due to a phenothiazine medication. Additionally, combining clemastine with a phenothiazine increases the risk of excessive drowsiness.
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Clemastine Drug Information

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