Cinryze is a drug that is given as an injection to prevent sudden attacks of swelling caused by hereditary angioedema. The recommended Cinryze dosage is the same for everyone, regardless of age. The drug can be administered by a healthcare provider or self-injected. It is injected into a vein over a 10-minute period every three or four days.
There is only one standard dose of Cinryze® (C1 esterase inhibitor), regardless of your age. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The usual recommended dose of Cinryze for the prevention of hereditary angioedema (HAE) attacks is 1000 units every three or four days. Each vial contains 500 units. Therefore, you will need two vials for each dose.
Once prepared for use, each vial contains 5 mL of medication (100 units per mL). Cinryze is given slowly at a rate of 1 mL per minute. Therefore, it will take 10 minutes to administer each dosage.
Some considerations to keep in mind during treatment with Cinryze include the following:
- Cinryze comes as a powder that is dissolved in Sterile Water for Injection to form a liquid. It is given as an injection into a vein (an intravenous, or IV, injection) every three or four days.
- The injections may be given by your healthcare provider or self-injected.
- If you will be self-administering this medication, your healthcare provider will teach you exactly how to use it. Make sure you completely understand these instructions before giving yourself injections.
- Each Cinryze dose is injected slowly over 10 minutes.
- You should wash your hands before preparing your dosage and work on a clean surface to prevent contamination.
- Inspect Cinryze vials after mixing, and only use the medication if it is colorless to slightly blue and free from particles.
- For the medication to work properly, it must be used as prescribed.
- If you are unsure about anything related to dosing with Cinryze, please talk with your healthcare provider, nurse, or pharmacist.