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Pediatric and Off-Label Indications for Botulinum Toxin Type A

Is Botulinum Toxin Type A Used in Children?

Botulinum toxin type A is approved to treat eye twitching or misaligned eyes in children as young as 12 years old. It is also approved to treat head and neck spasms (cervical dystonia) or severe sweating in children as young as 16 years old. Botulinum toxin type A is not approved for treating facial lines in children. Talk to your child's healthcare provider about the benefits and risks of using the drug in children.

Is Botulinum Toxin Type A Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend botulinum toxin type A for something other than the conditions discussed in this article. This is called an "off-label" use. At this time, off-label botulinum toxin type A uses include:
  • Cosmetic uses other than for frown lines between the eyebrows
  • Achalasia (a condition involving difficulty swallowing)
  • Drooling
  • Muscle spasms in children with cerebral palsy
  • Neurogenic bladder (bladder disorders caused by nerve problems)
  • Migraine headaches.

Botulinum Toxin Type A (Botox Cosmetic)

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