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Specific Conditions Botulinum Toxin Type A Treats and How It Works

Why Is Botulinum Toxin Type A Used for Head and Neck Spasms?

Botulinum toxin type A is also approved to treat cervical dystonia, a condition that involves unusual muscle spasms or contractions in the head or neck. Frequently, cervical dystonia causes an abnormal head position (often twisted to one side), abnormal head or neck movements, and neck pain.
Botulinum toxin type A can help decrease the severity of the abnormal head position and can help relieve neck pain. Although the drug will usually cause some improvement immediately, the full effects usually take about six weeks to develop and last for about three months.

Why Is Botulinum Toxin Type A Used for Eye Problems?

Sometimes, abnormal muscle spasms or contractions can affect the eye, causing eyelid twitches (known as blepharospasm) or misaligned eyes (known as strabismus). Botulinum toxin type A is approved for treating these conditions in people 12 years of age and older.

Why Is Botulinum Toxin Type A Used for Severe Sweating?

Sweating is a normal and necessary way for the body to cool itself. However, some people sweat more than is necessary. This is known medically as hyperhydrosis. While severe sweating may be caused by certain medications or medical conditions, it can also occur for no apparent reason (this is known as primary hyperhydrosis).
Botulinum toxin type A is approved to treat primary hyperhydrosis of the underarm that has not responded adequately to antiperspirants.

How Does Botulinum Toxin Type A Work?

Botulinum toxin type A is a toxin produced by Clostridium botulinum bacteria. The drug works by decreasing nerve signals that are sent to muscles, which causes the muscles to relax. Botulinum toxin type A enters nerve cells and inhibits the release of acetylcholine, a chemical that transmits signals from nerve to nerve. The actions of the drug are not permanent, and the muscle will eventually recover and return to its previous state.
For severe sweating, botulinum toxin type A works similarly, blocking the release of acetylcholine from the nerve cells that stimulate the sweat glands.

Botulinum Toxin Type A (Botox Cosmetic)

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