Alopecia Areata Causes

The primary cause of alopecia areata is an attack on the immune system. In this disease, white blood cells attack the rapidly growing cells in the hair follicles, which drastically slows down hair production. Scientists do not know how the disease causes the hair follicles to slow down hair production. However, they do suspect that people are genetically predisposed to alopecia areata.

What Causes Alopecia Areata?

Alopecia areata is considered to be an autoimmune disease, in which the immune system (which is designed to protect the body from foreign invaders such as viruses and bacteria) mistakenly attacks the hair follicles. This can lead to hair loss on the scalp and elsewhere.
 

Understanding the Immune System

In alopecia areata, white blood cells (which are part of the immune system) attack the rapidly growing cells in the hair follicles that make the hair. The affected hair follicles become small, which drastically slows down hair production. Fortunately, the stem cells that continually supply the follicle with new cells do not seem to be targeted, which means that the hair follicles always have the potential to grow more hair.
 

Do Genes Play a Role?

Scientists do not know how alopecia areata causes the hair follicles to slow down hair production. However, they do suspect that a combination of genes may predispose some people to alopecia areata. In those who are genetically predisposed, some type of trigger -- perhaps a virus or something in the person's environment -- brings on the attack against the hair follicles.
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD
Other Articles in This eMedTV Presentation