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Drug Interactions With Acitretin
If you use diabetes medications, tetracyclines, or isotretinoin in combination with acitretin, drug interactions could occur. Some of these interactions can increase your risk of dangerous side effects. To decrease your risk of developing potentially negative drug interactions, make sure to tell your healthcare provider about any other medications you are currently using.
Acitretin (Soriatane®) can potentially interact with several other medications. Some of these medicines that may lead to interactions with acitretin include:
- Alcohol of any kind
- Diabetes medications
- Isotretinoin (Accutane®, Amnesteem™, Claravis™, Sotret®)
- Methotrexate (Rheumatrex®, Trexall®)
- Phenytoin (Dilantin®, Phenytek®)
- Progestin-only "mini-pill" birth control pills, such as Ortho Micronor®, Errin®, or Jolivette®
- St. John's wort
- Tetracyclines, such as:
- Doxycycline (Periostat®, Vibramycin®)
- Minocycline (Minocin®)
- Tetracycline (Sumycin®)
More Details on Interactions With Acitretin
The following sections explain in detail the potentially negative interactions that can occur when acitretin is combined with any of the drugs listed above.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD