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Do I Take Drugs That React With Acitretin?

Progestin-Only Birth Control Pills
Women of childbearing potential must use two forms of birth control while taking acitretin (as well as one month before starting acitretin and for three years after stopping the medication). Progestin-only birth control pills are probably not effective enough for use in women taking acitretin (they are significantly less effective than combined oral contraceptives that contain both estrogen and a progestin), especially since acitretin makes progestin-only pills less effective.
 
It is unknown if acitretin makes other types of progestin-only contraceptives (such as injections or implants) less effective as well.
 
St. John's Wort
Do not self-treat yourself with St. John's wort while taking acitretin. If you have depression, you need to be evaluated by your healthcare provider. Also, St. John's wort can make birth control pills less effective, a problem that would be especially dangerous for women taking acitretin (due to the risk of birth defects).
 
Tetracyclines
Tetracyclines may increase the risk of pseudotumor cerebri (a certain type of high blood pressure in the cranium) in people who take acitretin. It is best to avoid taking acitretin with such antibiotics.
 
Vitamin A
Acitretin is related to vitamin A. Do not take vitamin A while on acitretin, as this could cause additive toxic effects.
 

Final Thoughts

It is possible that not all acitretin drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 

Acitretin Drug Information

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