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More Info on AbobotulinumtoxinA Indications

How Does AbobotulinumtoxinA Work?

AbobotulinumtoxinA contains a toxin produced by Clostridium botulinum bacteria. The drug works by decreasing nerve signals that are sent to muscles, which causes the muscles to relax. AbobotulinumtoxinA enters nerve cells and inhibits the release of acetylcholine, a chemical that transmits signals from nerve to nerve.
 
The actions of the drug are not permanent, and the muscle will eventually recover and return to its previous state.
 

Can Children Use AbobotulinumtoxinA?

AbobotulinumtoxinA is not approved for use in individuals under 18 years old. If you think your child may benefit from abobotulinumtoxinA injections, discuss the possible risks, as well as the benefits, with your child's healthcare provider.
 

Off-Label Uses

On occasion, your healthcare provider may recommend this medicine for something other than the conditions discussed in this article. This is called an "off-label" use. At this time, off-label uses of abobotulinumtoxinA include treating the following conditions:
 
  • Severe underarm sweating
  • Eyelid twitching or spasms (known medically as blepharospasm)
  • Misaligned eyes, such as crossed eyes (known medically as strabismus)
  • Achalasia (a condition involving difficulty swallowing)
  • Drooling
  • Muscle spasms in children with cerebral palsy
  • Neurogenic bladder (bladder disorders caused by nerve problems)
  • Migraine headaches.
     
Administering the drug for cosmetic uses other than frown lines between the eyebrows would be considered an off-label use of abobotulinumtoxinA as well.
 
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AbobotulinumtoxinA Drug Information

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