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Warnings and Precautions With AbobotulinumtoxinA

AbobotulinumtoxinA injections may not be suitable for everyone -- those who are allergic to cow's milk protein or any ingredient in the medicine should avoid it completely. Other precautions and warnings with abobotulinumtoxinA include being aware that the prescription medication can cause vision changes, dry eyes, and drug interactions.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider before you receive abobotulinumtoxinA (Dysport®) if you have:
 
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
You should also tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific AbobotulinumtoxinA Precautions and Warnings

Warnings and precautions to be aware of prior to receiving abobotulinumtoxinA include the following:
 
  • In rare cases, abobotulinumtoxinA can spread from the injection site to distant parts of the body, potentially causing serious problems. This is more likely to occur if the drug is used to treat spasticity in children. It should be noted that abobotulinumtoxinA is not approved for use in children.
     
  • The recommended dose of abobotulinumtoxinA is different from the recommended Botox® dosage, even though both medications contain botulinum toxin type A. The abobotulinumtoxinA dosage cannot be compared or converted to a dose of Botox.
     
  • The medication can cause allergic reactions. If you notice an unexplained rash, itching, wheezing, swelling, or difficulty breathing, tell your healthcare provider right away.
     
  • AbobotulinumtoxinA can cause difficulty swallowing, which may cause serious problems. This is more likely if you already have swallowing problems or if you have a neuromuscular disease.
     
  • AbobotulinumtoxinA contains albumin, a human protein. Theoretically, viruses or infectious proteins may be transmitted through albumin. However, there this has not been reported with an albumin product.
     
  • Sometimes, the medication can decrease your blinking reflex, especially if it is used near the eyes. This can dry out your eyes, increasing your risk of corneal abrasion or other eye problems. If your eyes seem to be dry, let your healthcare provider know right away.
     
  • Sometimes, abobotulinumtoxinA injections in the area near the eyes can cause vision changes. These changes are usually temporary.
     
  • AbobotulinumtoxinA can interact with a few different medications (see Drug Interactions With AbobotulinumtoxinA).
     
  • AbobotulinumtoxinA is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Dysport and Pregnancy).
     
  • It is not known if abobotulinumtoxinA passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Dysport and Breastfeeding).
     
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AbobotulinumtoxinA Drug Information

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