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Common Reactions to AbobotulinumtoxinA

Common Side Effects of AbobotulinumtoxinA

AbobotulinumtoxinA has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people given the drug were documented and compared to those that occurred in a similar group of people given a placebo (an injection with no active ingredient). This way, it is possible to see what side effects occurred, how often they appeared, and how they compare to the group receiving the placebo.
In studies using abobotulinumtoxinA for cosmetic purposes (to improve the appearance of lines between the eyebrows), common side effects included:
  • Common cold symptoms, such as a runny nose and sore throat -- in up to 10 percent of people
  • Headache -- up to 9 percent
  • Upper respiratory tract infection -- up to 3 percent
  • Pain at the injection site -- up to 3 percent
  • Skin reaction at the injection site -- up to 3 percent
  • Swollen eyelids -- up to 2 percent
  • Droopy eyelids -- up to 2 percent
  • Nausea -- up to 2 percent
  • Sinus infection -- up to 2 percent
  • Blood in the urine -- up to 2 percent.
In studies using abobotulinumtoxinA for treating cervical dystonia (a condition involving muscle spasms of the head and neck), the most common side effects included:
  • Muscle weakness -- in up to 56 percent of people
  • Dry mouth -- up to 39 percent
  • Difficulty swallowing -- up to 39 percent
  • Voice change -- up to 28 percent
  • Discomfort at the injection site -- up to 22 percent
  • Eye "disorders" (such as blurred vision or droopy eyelids) -- up to 17 percent
  • Fatigue -- up to 12 percent
  • Impaired facial movement -- up to 11 percent
  • Headache -- up to 11 percent.
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AbobotulinumtoxinA Drug Information

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